Home-Based Rehabilitation With Frenkel’s Exercises for Adrenomyeloneuropathy: A Case Report

Publication

Affiliations

Nana-r Home-Visit Nursing Development Center

Journal

Cureus

Year / Volume / Issue / Pages

2025 / 17 / 3 / e80878

DOI

10.7759/cureus.80878

Publisher page

Open publisher page

Repository file

Manuscript type

Author Accepted Manuscript

Repository publication date

2026-08-20

License

Creative Commons Attribution 4.0 International

PDF

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Abstract

Adrenoleukodystrophy (ALD) encompasses a spectrum of X-linked genetic disorders, including the adult-onset adrenomyeloneuropathy (AMN) phenotype. We report the case of a 32-year-old male with AMN and examine the impact of a tailored home-based rehabilitation regimen, specifically employing Frenkel’s exercises. The patient displayed classic AMN symptoms, including spastic paraparesis, peripheral neuropathy, and urinary disturbances. Initial assessments revealed significant ataxia-related impairments, particularly in gait, stance, and heel-shin slide. A home-visit nurse collaborated with the patient to develop and implement a personalized regimen utilizing Frenkel’s exercises. Over one month, the patient demonstrated remarkable improvement, reducing his Scale for the Assessment and Rating of Ataxia score from 10 to 5. Detailed analysis revealed specific enhancements in gait, stance, and fine motor control, aligning with the goals of Frenkel’s exercises. These findings suggest that Frenkel’s exercises can be a valuable addition to AMN rehabilitation, addressing ataxia-related motor deficits. While recognizing AMN’s complexity and individual variability, further research is essential to refine rehabilitation strategies. Long-term follow-up studies are needed to assess intervention sustainability and its impact on the ALD spectrum’s overall disease progression and quality of life.

Keywords

adrenomyeloneuropathy (amn) · frenkel’s exercises · home-based care · home-visit nurse · rehabilitation · x-linked adrenoleukodystrophy (x-ald)